There have been two Randomized Clinical Trials (RCTs) of OEI with PTSD. The first of these involved a group of mixed trauma survivors, randomly assigned to either a treatment or delayed treatment control group. Traumas included: Holding a spouse after suicide by gunshot, cutting down the body of someone who had hung himself (known to the survivor), experiencing a violent rape, being the victim of an attempted homicide, waking to see a close friend dead of a drug overdose, and motor vehicle accidents. OEI treatment involved only three one-hour sessions of OEI, using only one of the OEI techniques (‘switching’). A recent journal article in which this study is reported:
Bradshaw, R. A., McDonald, M. J., Grace, R., Detwiler, L., & Austin, K. (2014). A randomized clinical trial of Observed & Experiential Integration (OEI): A simple, innovative intervention for affect regulation in clients with PTSD. Traumatology, 20(3), 161-171. http://dx.doi.org/10.1037/h0099401
The most recent RCT was a mixed method, comparative experimental treatment outcome study. It involved 25 women with PTSD following sexual assaults, spanned 18 months, and included qEEG assessments with script-driven symptom provocation on four occasions. The details of this study are provided in the first research report down the margin to the right. A list of OEI publications to date (including theses and conference papers) is included in that summary.
For more detailed information about OEI (origins & history, techniques, applications, neurobiological mechanisms, and case examples), please refer to a 68-page APA journal article from 2011:
Bradshaw, R. A., Cook, A., & McDonald, M. J. (2011). Observed & experiential integration (OEI): Discovery and development of a new set of trauma therapy techniques. Journal of Psychotherapy Integration, 21(2), 104–171. https://doi.org/10.1037/a0023966